Dhh-cre
012929 FVB(Cg)-Tg(Dhh-cre)1Mejr/J The Dhh-cre transgene harbors a nuclear-localized Cre recombinase gene under control of the mouse desert hedgehog ( Dhh ) promoter/regulatory regions. These transgenic mice may be useful in generating cre -inducible mutations in Sertoli cell precursors (testes development/male germline), endothelial cells, and Schwann cells of the peripheral nervous system. WebTsc1 flox/flox-GFAP-Cre (Tsc1 GFAP CKO) mice were generated in our laboratories using Cre-LoxP methodology. To inactivate Tsc1 gene expression in glial fibrillary acidic …
Dhh-cre
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WebMar 21, 2024 · (C) Western blot of sciatic nerve and neurofibroma tumors of Nf1 fl/fl;Dhh Cre and P2ry14-/-;Nf1 fl/fl;Dhh Cre mice show decrease in P2ry14 expression upon P2ry14 knockdown (1- to 0.1-fold decrease in sciatic nerve and 1- to 0.2-fold decrease in neurofibroma tissue). WebApr 4, 2024 · BIG1 knockout mice (BIG1 fl/fl; Dhh-Cre) showed a decrease in the relative amounts of MPZ in inner myelin sheaths (Fig. 5, A and B). Similar results are obtained from Arf1 knockout mice (Arf1 fl/fl; Dhh-Cre; Fig. 5, C and D), suggesting that BIG1 and Arf1 constitute one of the transporting systems of the myelin component. It is likely that BIG1 ...
WebThe genotyping protocol (s) presented here have been optimized for reagents and conditions used by The Jackson Laboratory (JAX). To genotype animals, JAX … WebJul 5, 2024 · The Dhh cre transgene results in Cre recombinase expression under the Desert hedgehog promoter at approximately embryonic day (E) 12.5 in SC precursors 10.
WebNational Center for Biotechnology Information WebFigure 1 . Loss of Ninj2 in SCs promotes precocious myelination. (A-B) Electron microscopic examination of the sciatic nerve from WT or Dhh cre/+;Ninj2 fl/fl mice from postnatal day 0 to 60 as indicated. Scale bar, 2 µm. (C-D) The myelinated axon numbers and the percentages of bundle area were quantified.(E-G) Electron microscopic examination of …
WebSciatic nerves were dissected from P11 Dhh-Cre + LoxpRosa + (A,B) pups as well as Dhh-Cre − LoxpRosa + (C) littermate controls, processed for bluo-gal staining, and examined by electron microscopy.
WebA multiplicação dos pães e peixes - Depois disso, partiu Jesus para o outro lado do mar da Galileia, que é o de Tiberíades. E grande multidão o seguia, porque via os sinais que operava sobre os enfermos. E Jesus subiu ao monte e assentou-se ali com os seus discípulos. E a Páscoa, a festa dos judeus, estava próxima. Então, Jesus, levantando os … income tax india formWebSep 7, 2024 · Next, we assessed the extent of myelination by electron microscopy (EM). Surprisingly, P5 Dhh Cre:Tsc1 KO nerves exhibited a strong reduction in myelinated fibers due to an arrest of most SCs at the … income tax india form 16 downloadWebBe prepared to conduct a site visit when necessary and assess implementation of infection control strategies. Use the CRE self-assessment tool (PDF) or the Core Infection … income tax india forms downloadWebJul 1, 2012 · Transgenic mice carrying all 3 transgenes [Dhh-Cre; Nf1 flox /+; Pten flox /+ (Nf1-het/Pten-het)] were interbred to generate both experimental and control cohorts . Complete inactivation of Pten in Schwann cells and/or their precursor cells alone can also contribute to enlarged dorsal root ganglia but at a lower penetrance (Supplementary Fig. … income tax india form 10fhttp://en.modelorg.com/upload/pdf/Dhh-Cre.en-us.pdf income tax india form 16WebWe tested the effects of PLX3397, a dual kit/fms kinase inhibitor that blocks macrophage infiltration, in the Dhh-Cre; Nf1(flox/flox) mouse model of GEM grade I neurofibroma. In … income tax india helpline numberWebHere, we report that the same Dhh-Cre driver line can efficiently label melanocytes when used in a pure FVB/N background together with the fluorescent instead of the non … income tax india government