Web1. GRASPs and golgins are both types of proteins that are crucial for maintaining the structure and function of the Golgi apparatus. GRASPs (Golgi reassembly stacking proteins) play a crucial role in the formation and maintenance of Golgi stacks, while golgins are involved in tethering and organizing transport vesicles that move between the stacks. WebSep 9, 2024 · Figure 1. Golgi proteins involved in vesicles transportation. (A) Both of oligomeric Golgi (COG ... in formation and degradation of autophagosomes, while p230, WW domain containing adaptor with …
[PDF] Mapping the Functional Domains of the Golgi Stacking …
WebNational Center for Biotechnology Information WebFor example, GRASP65 (Golgi reassembly and stacking proteins 65), distributed on the peripheral membrane of the Golgi apparatus, interacts with the actin-binding protein Mena and leads to its own homologous oligomerization, which mediates the stacking of the Golgi cisternae and ribbon formation [122,123,124]. the bradford exchange headquarters
New structural insights into Golgi Reassembly and Stacking Protein ...
WebNov 26, 2024 · Golgi reassembly and stacking protein 65 (GRASP65), which has been involved in cancer progression, is associated with tumor growth and cell apoptosis. … WebMar 7, 2008 · There are two processes during Golgi disassembly: unstacking and vesiculation. Unstacking is mediated by two mitotic kinases, cdc2 and plk, which phosphorylate the Golgi stacking protein GRASP65 and thus disrupt the oligomer of this protein. Vesiculation is mediated by the COPI budding machinery ARF1 and the … WebThe PA1-076 immunogen is a synthetic peptide corresponding to residues P(419) A S K V P T T V E D R V S D(433) of rat GRASP55 protein. This peptide is available for neutralization controls as PEP-295. GRASP55 is a PDZ containing protein involved in the stacking of golgi cisternea in a cell-free system. the bradford exchange harry potter collection