Phospho-creb ser133
WebCREB serine 133 (Ser-133) residue is phosphorylated by various kinases and this phosphorylation promotes the interaction of CREB with a number of transcription coactivators, especially the histone acetyltransferases CREB-binding protein (CBP) or … WebAnti-phospho-CREB (Ser133) Antibody, clone 10E9 is a Mouse Monoclonal Antibody for detection of phospho-CREB (Ser133) also known as active transcription factor CREB & …
Phospho-creb ser133
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WebAnti-CREB (Ser133) Antibody. Our Anti-CREB (Ser133) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects rat CREB (Ser133) and is antigen affinity purified from pooled serum. It is great for use in WB, IHC. Immunolabeling of a section of mouse piriform cortex labeled with Anti-Phospho-Ser133 ... WebUpon phosphorylation, CREB forms a functionally active dimer that binds the cis-acting CRE element within the promoters of target genes. 220,221 Immediate-early genes, such as c-fos, Bcl-2, the IAPs, ... sustained phosphorylation of CREB at Ser133 and CREB activation.
WebMar 29, 2024 · The CREB binding domain, referred to as KIX, is α helical and binds to an unstructured kinase-inducible domain in CREB following phosphorylation of CREB at Ser … WebAbstract. Cyclic AMP response element binding protein (CREB) is a constitutive transcription factor that activates transcription following stimulus-dependent phosphorylation at …
WebMar 21, 2024 · CREB1 (CAMP Responsive Element Binding Protein 1) is a Protein Coding gene. Diseases associated with CREB1 include Histiocytoma, Angiomatoid Fibrous and Melanoma Of Soft Tissue . Among its related pathways are MyD88 dependent cascade initiated on endosome and Calmodulin induced events . WebUse Anti-phospho-CREB (Ser133) Antibody (rabbit polyclonal antibody) is highly published and validated in EMSA, IHC,IHC (P), IP, WB to detect phospho-CREB (Ser133) also known …
WebAnti-CREB (phospho Ser133) antibody (GTX130379) GeneTex Back Primary Antibodies Secondary Antibodies Antibody Panels ELISA Antibody Pairs & Kits Isotype Controls Proteins & Peptides Slides Lysates Serums & Plasmas Reagents Research Kits Research Tools Back Cancer Tumor Markers Neuroscience Cell Biology Metabolism Epigenetics Cardiovascular
WebApr 9, 2024 · Because PKA-mediated phosphorylation of CREB on Ser133 increases CREB interaction with P300/CBP ... of FFSS in vitro or wheel running both induce secretion of PGE2 and nuclear accumulation of phospho-CREB and CRTC1 and promote COX-2-dependent expression of Prg4 in articular chondrocytes, it seems likely that administration of FFSS in … destiny 2 sealed ahamkara grasps buildWebMar 29, 2024 · The CREB binding domain, referred to as KIX, is α helical and binds to an unstructured kinase-inducible domain in CREB following phosphorylation of CREB at Ser-133. Phospho-Ser-133 forms direct contacts with residues in KIX, and these contacts are further stabilized by hydrophobic residues in the kinase-inducible domain which flank … destiny 2 screen tearing fixWebThis antibody recognizes CREB protein phosphorylated at serine 133 and ATF1 phosphorylated at serine 63. The antibody was purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography. Aliquot and freeze in liquid nitrogen. Antibody can be stored frozen at -80°C for up to 1 year. destiny 2 scythe weaponWebProduct Information. 28792-1-AP targets Phospho-CREB1 (Ser133) in WB, IHC, ELISA applications and shows reactivity with Human samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. chudy isidienuWebCREB is activated by phosphorylation at Ser133 by various signaling pathways, including Erk, Ca 2+, and stress signaling. Some of the kinases involved in phosphorylating CREB at Ser133 are p90RSK, MSK, CaMKIV, and MAPKAPK-2 (7-9). Lonze, B.E. et al. (2002) Neuron 34, 371-85. Lee, M.M. et al. (1999) J Neurosci Res 55, 702-12. destiny 2 search for nightfall groupWebThe authors' previous reports showed that blocking the CREB binding site at Ser 133 inhibited the expression of target genes, which related to the progression of some tumors. In this study, the authors investigated the role of phosphorylated CREB (pCREB) at Ser133 in renal cell carcinoma (RCC) growth and metastases. chudy dressWebPhospho-CREB (Ser133) Polyclonal Antibody Catalog Number:44-298G Product Data Sheet Background/Target Information ... Phosphorylation occurs via p44/42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription ... chudy grubas