Phosphohistidine phosphatase sixa
WebSixA was first reported to be a phosphohistidine phosphatase that dephosphorylates the histidine-containing phosphotransfer domain of the E. coli sensor kinase ArcB ( 32 , 41 ), … WebA widely conserved phosphohistidine phosphatase was identified in Escherichia coli twenty years ago but remains relatively understudied. This bacterial protein is called signal …
Phosphohistidine phosphatase sixa
Did you know?
WebJan 1, 2024 · We show that the phosphatase SixA dephosphorylates the phosphocarrier protein NPr and that the reaction proceeds through phosphoryl transfer from a histidine on NPr to a histidine on SixA. In addition, we show that Escherichia coli lacking SixA are outcompeted by wild-type E. coli in the context of commensal colonization of the mouse … WebJan 1, 2024 · A secondary lymphoid organ, Spleen hosts highly dormant hematopoietic stem cells. Molecular pathways essential for splenic HSC maintenance, and regulating their function in the spleen at a steady state, remain elusive.
WebNov 10, 2006 · The structure of phosphohistidine phosphatase (PHPT1) has been determined to a resolution of 1.9Å using multiple-wavelength anomalous dispersion methods and Histidine 53 is proposed to play a major role in histidine dephosphorylation based on these observations and previous mutational studies. WebResearch in the field of protein-bound phosphohistidine phosphorylation has been hampered by the difficulties in analysis and detection of phosphohistidine. Therefore a screening method was developed primarily for the analysis of phosphohistidine phosphatase 1 (PHPT1) activity. Methods. A highly positively charged substrate, Ac-Val …
WebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. A single protein target of SixA has been reported to … WebJul 4, 2024 · Distributed in oceans and freshwater globally ( Van Soest et al., 2012 ), these efficient filter feeders play an essential role in linking pelagic and benthic environments by consuming particulate organic matter and dissolved organic matter ( Yahel et al., 2003; de Goeij et al., 2013 ).
WebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. …
WebJan 1, 2007 · SixA was found to exhibit protein histidine phosphatase activity involving the dephosphorylation of phosphohistidine at the HPt domain C terminus of sensor kinase … churches toowoombaWebNov 10, 2006 · SixA shows structural homology to the well studied family of arginine-histidine-glycine (RHG) phosphatases but no sequence homology to PHPT1. Mammalian phosphohistidine phosphatase (PHPT1) was first identified and characterized as a 14-kDa protein in 2002 (7, 8). device location sv prefab tier 5WebThe widespread conservation of SixA, and its coincidence with the phosphotransferase system studied here, suggests that this dephosphorylation mechanism may be conserved in other bacteria. Histidine phosphorylation is a posttranslational modification that alters protein function and also serves as an intermediate of phosphoryl transfer. Although … churches townsvilleWebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. … churches townsend tnWebMar 1, 2002 · Such a phosphohistidine phosphatase, if present, should also serve as a modulator for the His-Asp phosphorelay. In this study, we intended to find such a … churches tourism agency in usaWebJan 1, 2024 · SixA was first reported to be a phosphohistidine phosphatase that dephosphorylates the histidine-containing phosphotransfer domain of the E. coli sensor … churches tour scheduleWebNov 16, 2024 · The phosphohistidine phosphatase SixA dephosphorylates the phosphocarrier NPr. Jane E. Schulte 1,2, Manuela Roggiani 2, Hui Shi 2,3, Jun Zhu 4, and Mark Goulian 2,5 * device list on iphone