Siglec 10 antibody
WebAK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). Preclinical studies have demonstrated that monotherapy treatment with a … WebBuy rabbit polyclonal antibody to SIGLEC10 (A54002). Applications: ELISA, IP and WB. Reactivity: Human and Rat. ️ Low Prices ️ 100% Guarantee. Useful Links. 01223 298 ...
Siglec 10 antibody
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WebSialic acid–binding immunoglobulin-like lectin 8 (Siglec-8) is an inhibitory receptor that is selectively expressed on mature eosinophils and mast cells, with low expression on basophils. 5,23 ... WebPRO940 antibody, SIGLEC-10 antibody, SLG2 antibody, Siglecg antibody, SIGLEC10 antibody, slg2 antibody, pro940 antibody, siglec-10 antibody, sialic acid binding Ig like …
WebSIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition … WebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane …
WebJun 10, 2024 · High infiltration of Siglec-10 hi TAMs was associated with impaired CD8 + T cell function in HCC. Of note, blocking Siglec-10 with the competitive binding antibody … WebThe 5G6 monoclonal antibody specifically recognizes Sialic acid-binding Ig-like lectin 10 (Siglec-10). Siglec-10 is a type I transmembrane glycoprotein encoded by SIGLEC10 …
WebMar 21, 2024 · SIGLEC10 (Sialic Acid Binding Ig Like Lectin 10) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated …
WebNov 10, 2024 · AK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). By targeting Siglec … east riding school holidayWebNov 29, 2024 · The anti-Siglec-10 (clone 5G6) was used as a blocking antibody to inhibit the CD24-Siglec-10 axis, and robustly improved the phagocytosis of tumour cells by … cumberland county nj dumpWebJul 31, 2024 · The blockade of Siglec-10 using monoclonal antibodies augmented the phagocytic ability of macrophages, thereby confirming a role for Siglec-10 in inhibiting … east riding school holidays 2023/2024WebSIGLEC 10 antibody. Siglec G antibody. Siglec-like protein 2 antibody. SIGLEC10 antibody. Siglecg antibody. SLG2 antibody : Protein information supplied by UniProt . Accessories. … east riding school menuWebMay 20, 2024 · Indeed, B-cell activation by antibodies to the B-cell receptor IgD is dramatically suppressed by conjugation of anti-IgD with high affinity ligands of a B-cell … cumberland county nj elections 2022WebSpecificity. Clone 5G6 specifically recognizes human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and member of the Ig superfamily, expressed by … east riding school holsWebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane protein that has four extracellular Ig-like domains, a transmembrane region, and a cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (2). east riding smt